Characterization of a Novel Dithiocarbamate Glutathione Reductase Inhibitor and Its Use as a Tool to Modulate Intracellular Glutathione

Thiol redox state (TRS) is an important parameter to reflect intracellular oxidative stress and is associated with various normal and abnormal biochemical processes. Agents that can be used to increase intracellular TRS will be valuable tools in TRS-related research. Glutathione reductase (GR) is a...

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Autori principali: Seefeldt, Teresa, Zhao, Yong, Chen, Wei, Raza, Ashraf S., Carlson, Laura, Herman, Jocqueline, Stoebner, Adam, Hanson, Sarah, Foll, Ryan, Guan, Xiangming
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
Enzyme Catalysis and Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631970/
https://ncbi.nlm.nih.gov/pubmed/19049979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802683200
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