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Evaluation of a Dithiocarbamate Derivative as an Inhibitor of Human Glutaredoxin-1
CONTEXT: Glutaredoxins (GRX) are involved in the regulation of thiol redox state. GRX-1 is a cytosolic enzyme responsible for the catalysis of deglutathionylation of proteins. To date, very few inhibitors of GRX-1 have been reported. OBJECTIVE: The objective of this paper is to report 2-acetylamino-...
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| Izdano u: | J Enzyme Inhib Med Chem |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4310727/ https://ncbi.nlm.nih.gov/pubmed/22299579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/14756366.2011.649267 |
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