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Characterization of a Novel Dithiocarbamate Glutathione Reductase Inhibitor and Its Use as a Tool to Modulate Intracellular Glutathione

Thiol redox state (TRS) is an important parameter to reflect intracellular oxidative stress and is associated with various normal and abnormal biochemical processes. Agents that can be used to increase intracellular TRS will be valuable tools in TRS-related research. Glutathione reductase (GR) is a...

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Detalhes bibliográficos
Main Authors: Seefeldt, Teresa, Zhao, Yong, Chen, Wei, Raza, Ashraf S., Carlson, Laura, Herman, Jocqueline, Stoebner, Adam, Hanson, Sarah, Foll, Ryan, Guan, Xiangming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631970/
https://ncbi.nlm.nih.gov/pubmed/19049979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802683200
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