Small GTPase Determinants for the Golgi Processing and Plasmalemmal Expression of Human Ether-a-go-go Related (hERG) K(+) Channels

The pro-arrhythmic Long QT syndrome (LQT) is linked to 10 different genes (LQT1–10). Approximately 40% of genotype-positive LQT patients have LQT2, which is characterized by mutations in the human ether-a-go-go related gene (hERG). hERG encodes the voltage-gated K(+) channel α-subunits that form the...

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Autors principals: Delisle, Brian P., Underkofler, Heather A. S., Moungey, Brooke M., Slind, Jessica K., Kilby, Jennifer A., Best, Jabe M., Foell, Jason D., Balijepalli, Ravi C., Kamp, Timothy J., January, Craig T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Membrane Transport, Structure, Function, and Biogenesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631954/
https://ncbi.nlm.nih.gov/pubmed/19029296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807289200
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