Muscleblind-Like Proteins : Similarities and Differences in Normal and Myotonic Dystrophy Muscle

In myotonic dystrophy, muscleblind-like protein 1 (MBNL1) protein binds specifically to expanded CUG or CCUG repeats, which accumulate as discrete nuclear foci, and this is thought to prevent its function in the regulation of alternative splicing of pre-mRNAs. There is strong evidence for the role o...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Holt, Ian, Jacquemin, Virginie, Fardaei, Majid, Sewry, Caroline A., Butler-Browne, Gillian S., Furling, Denis, Brook, J. David, Morris, Glenn E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631334/
https://ncbi.nlm.nih.gov/pubmed/19095965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080520
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares