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Changes in Myotonic Dystrophy Protein Kinase Levels and Muscle Development in Congenital Myotonic Dystrophy

Myotonic dystrophy (DM1) is caused by the expansion of a CTG repeat in the noncoding region of a protein kinase, DMPK, expressed in skeletal and cardiac muscles. The aim of the present study was to determine the effects of very large CTG expansions on DMPK expression and skeletal muscle development....

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Bibliografiske detaljer
Main Authors: Furling, Denis, Lam, Le Thanh, Agbulut, Onnik, Butler-Browne, Gillian S., Morris, Glenn E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2003
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868110/
https://ncbi.nlm.nih.gov/pubmed/12598332
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