A Controlled Pharmacogenetic Trial of Sibutramine on Weight Loss and Body Composition in Obese or Overweight Adults

BACKGROUND/ AIM: Weight loss in response to sibutramine is highly variable. We assessed the association of specific markers of polymorphisms of candidate a2A adrenoreceptor, 5-HT transporter and GNβ3 genes and weight loss with sibutramine. METHODS: We conducted a randomized, double-blind, pharmacoge...

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Detalhes bibliográficos
Main Authors: Grudell, April B.M., Sweetser, Seth, Camilleri, Michael, Eckert, Deborah J., Vazquez-Roque, Maria I., Carlson, Paula J., Burton, Duane D., Braddock, Autumn E., Clark, Matthew M., Graszer, Karen M., Kalsy, Sarah A., Zinsmeister, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629484/
https://ncbi.nlm.nih.gov/pubmed/18725220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.07.009
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