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IFN-γ, IL-4 and IL-13 modulate responsiveness of human airway smooth muscle cells to IL-13
BACKGROUND: IL-13 is a critical mediator of allergic asthma and associated airway hyperresponsiveness. IL-13 acts through a receptor complex comprised of IL-13Rα1 and IL-4Rα subunits with subsequent activation of signal transducer and activator of transcription 6 (STAT6). The IL-13Rα2 receptor may a...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2628656/ https://ncbi.nlm.nih.gov/pubmed/19116009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-9-84 |
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