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IL-18 Induces Emphysema and Airway and Vascular Remodeling via IFN-γ, IL-17A, and IL-13

Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation, alveolar destruction, and airway and vascular remodeling. However, the mechanisms that lead to these diverse alterations have not been defined. Objectives: We hypothesized that IL-18 plays a central rol...

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書誌詳細
主要な著者: Kang, Min-Jong, Choi, Je-Min, Kim, Bo Hye, Lee, Chang-Min, Cho, Won-Kyung, Choe, Gina, Kim, Do-Hyun, Lee, Chun Geun, Elias, Jack A.
フォーマット: Artigo
言語:Inglês
出版事項: American Thoracic Society 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373071/
https://ncbi.nlm.nih.gov/pubmed/22383501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201108-1545OC
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