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IFN‐γ(+)IL‐17(+)Th17 cells regulate fibrosis through secreting IL‐21 in systemic scleroderma

This study aimed to explore the function of IFN‐γ(+)IL‐17(+)Th17 cells on fibrosis in systemic scleroderma (SSc). Blood and skin samples were collected from 20 SSc cases and 10 healthy individuals. The percentage of IFN‐γ(+)IL‐17(+)Th17 cells was detected using flow cytometry. The in vitro induction...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Xing, Xiaojing, Li, Anqi, Tan, Hong, Zhou, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7753990/
https://ncbi.nlm.nih.gov/pubmed/33157566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15266
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