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Secretion of IFN-γ but Not IL-17 by CD1d-Restricted NKT Cells Enhances Rejection of Skin Grafts Expressing Epithelial Cell-Derived Antigen

NKT cells are key regulators of autoimmunity, tumor immune surveillance, and the immune response to pathogens. The role of NKT cells in regulating adaptive immunity to cutaneous Ags is largely unknown. This study explores the role of CD1d-restricted NKT cells in cross-priming of CD8 effector T cells...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mattarollo, Stephen R., Yong, Michelle, Tan, Lieven, Frazer, Ian H., Leggatt, Graham R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921625/
https://ncbi.nlm.nih.gov/pubmed/20410490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903730
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