IL-18 Induces Emphysema and Airway and Vascular Remodeling via IFN-γ, IL-17A, and IL-13

Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation, alveolar destruction, and airway and vascular remodeling. However, the mechanisms that lead to these diverse alterations have not been defined. Objectives: We hypothesized that IL-18 plays a central rol...

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Autores principales: Kang, Min-Jong, Choi, Je-Min, Kim, Bo Hye, Lee, Chang-Min, Cho, Won-Kyung, Choe, Gina, Kim, Do-Hyun, Lee, Chun Geun, Elias, Jack A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2012
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373071/
https://ncbi.nlm.nih.gov/pubmed/22383501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201108-1545OC
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