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IL-18 Induces Emphysema and Airway and Vascular Remodeling via IFN-γ, IL-17A, and IL-13

Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation, alveolar destruction, and airway and vascular remodeling. However, the mechanisms that lead to these diverse alterations have not been defined. Objectives: We hypothesized that IL-18 plays a central rol...

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Bibliografski detalji
Glavni autori: Kang, Min-Jong, Choi, Je-Min, Kim, Bo Hye, Lee, Chang-Min, Cho, Won-Kyung, Choe, Gina, Kim, Do-Hyun, Lee, Chun Geun, Elias, Jack A.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373071/
https://ncbi.nlm.nih.gov/pubmed/22383501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201108-1545OC
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