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MAP kinases mediate interleukin-13 effects on calcium signaling in human airway smooth muscle cells

Interleukin-13 (IL-13) has been strongly implicated in the pathogenesis of allergic asthma through animal models that have shown that IL-13 is both necessary and sufficient to cause airway hyperresponsiveness (AHR). Airway smooth muscle (ASM) is a primary effector of AHR, and IL-13 increases the res...

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Detalhes bibliográficos
Main Authors: Moynihan, Barry, Tolloczko, Barbara, Michoud, Marie-Claire, Tamaoka, Meiyo, Ferraro, Pasquale, Martin, James G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494781/
https://ncbi.nlm.nih.gov/pubmed/18441092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00457.2007
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