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SERPINE1 (PAI-1) is deposited into keratinocyte migration “trails” and required for optimal monolayer wound repair

Cutaneous tissue injury, both in vivo and in vitro, initiates activation of a “wound repair” transcriptional program. One such highly induced gene encodes plasminogen activator inhibitor type-1 (PAI-1, SERPINE1). PAI-1-GFP, expressed as a fusion protein under inducible control of +800 bp of the woun...

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Bibliographische Detailangaben
Hauptverfasser: Providence, Kirwin M., Higgins, Stephen P., Mullen, Andrew, Battista, Ashley, Samarakoon, Rohan, Higgins, Craig E., Wilkins-Port, Cynthia E., Higgins, Paul J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628461/
https://ncbi.nlm.nih.gov/pubmed/18386027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00403-008-0845-2
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