Genetic elimination of prothrombin in adult mice is not compatible with survival and results in spontaneous hemorrhagic events in both heart and brain

Lignende værker

• Limiting prothrombin activation to meizothrombin is compatible with survival but significantly alters hemostasis in mice
  af: Shaw, Maureen A., et al.
  Udgivet: (2016)
• Genetic diminution of circulating prothrombin ameliorates multiorgan pathologies in sickle cell disease mice
  af: Arumugam, Paritha I., et al.
  Udgivet: (2015)
• The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A
  af: Flick, Matthew J., et al.
  Udgivet: (2011)
• Tumor cell–associated tissue factor and circulating hemostatic factors cooperate to increase metastatic potential through natural killer cell–dependent and–independent mechanisms
  af: Palumbo, Joseph S., et al.
  Udgivet: (2007)
• Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense
  af: Prasad, Joni M., et al.
  Udgivet: (2015)