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Method to Screen Substrates of Apical Sodium-Dependent Bile Acid Transporter
Human apical sodium-dependent bile acid transporter (hASBT) is a potential prodrug target under study. Development of prodrugs that target hASBT may yield compounds with low solubility and/or susceptibility to hydrolysis. A transport uptake method is needed that increases compound solubility and avo...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer US
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2628203/ https://ncbi.nlm.nih.gov/pubmed/19085111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-008-9069-9 |
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