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Influence of Charge and Steric Bulk in C-24 Region on the Interaction of Bile Acids with Human Apical Sodium Dependent Bile Acid Transporter (hASBT)

The human Apical Sodium-dependent Bile Acid Transporter (hASBT) is a potential target for drug delivery, but an understanding of hASBT substrate requirements is limited. The objective of this study was to evaluate the influence of ionic character and steric bulk in the C-24 region of bile acid conju...

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Autores principales: Balakrishnan, Anand, Wring, Stephen A., Coop, Andrew, Polli, James E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526283/
https://ncbi.nlm.nih.gov/pubmed/16749860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp0600135
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