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Artificial ligand binding within the HIF2α PAS-B domain of the HIF2 transcription factor
The hypoxia-inducible factor (HIF) basic helix–loop–helix Per-aryl hydrocarbon receptor nuclear translocator (ARNT)-Sim (bHLH-PAS) transcription factors are master regulators of the conserved molecular mechanism by which metazoans sense and respond to reductions in local oxygen concentrations. In hu...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2626723/ https://ncbi.nlm.nih.gov/pubmed/19129502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808092106 |
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