Activity of Metal-Responsive Transcription Factor 1 by Toxic Heavy Metals and H(2)O(2) In Vitro Is Modulated by Metallothionein

Metallothioneins are small, cysteine-rich proteins that avidly bind heavy metals such as zinc, copper, and cadmium to reduce their concentration to a physiological or nontoxic level. Metallothionein gene transcription is induced by several stimuli, notably heavy metal load and oxidative stress. Tran...

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Опубликовано в::	Mol Cell Biol
Главные авторы:	Zhang, Bo, Georgiev, Oleg, Hagmann, Michael, Günes, Çagatay, Cramer, Mirjam, Faller, Peter, Vasák, Milan, Schaffner, Walter
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 2003
Предметы:	Transcriptional Regulation
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262672/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14612393/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.23.8471-8485.2003
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