Target gene search for the metal-responsive transcription factor MTF-1

Activation of genes by heavy metals, notably zinc, cadmium and copper, depends on MTF-1, a unique zinc finger transcription factor conserved from insects to human. Knockout of MTF-1 in the mouse results in embryonic lethality due to liver decay, while knockout of its best characterized target genes,...

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Main Authors: Lichtlen, P., Wang, Y., Belser, T., Georgiev, O., Certa, U., Sack, R., Schaffner, W.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2001
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC31279/
https://ncbi.nlm.nih.gov/pubmed/11266553
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