Knockout of ‘metal-responsive transcription factor’ MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis

‘Metal-responsive transcription factor-1’ (MTF-1), a zinc finger protein, is conserved from mammals to insects. In the mouse, it activates metallothionein genes and other target genes in response to several cell stress conditions, notably heavy metal load. The knockout of MTF-1 in the mouse has an e...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	EMBO J
Autori principali:	Egli, Dieter, Selvaraj, Anand, Yepiskoposyan, Hasmik, Zhang, Bo, Hafen, Ernst, Georgiev, Oleg, Schaffner, Walter
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2003
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140060/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12505988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg012
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!