Knockout of ‘metal-responsive transcription factor’ MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis

‘Metal-responsive transcription factor-1’ (MTF-1), a zinc finger protein, is conserved from mammals to insects. In the mouse, it activates metallothionein genes and other target genes in response to several cell stress conditions, notably heavy metal load. The knockout of MTF-1 in the mouse has an e...

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書目詳細資料

發表在:	EMBO J
Principais autores:	Egli, Dieter, Selvaraj, Anand, Yepiskoposyan, Hasmik, Zhang, Bo, Hafen, Ernst, Georgiev, Oleg, Schaffner, Walter
格式:	Artigo
語言:	Inglês
出版:	Nature Publishing Group 2003
主題:	Articles
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140060/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12505988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg012
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