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Nonhomologous-End-Joining Factors Regulate DNA Repair Fidelity during Sleeping Beauty Element Transposition in Mammalian Cells

Herein, we report that the DNA-dependent protein kinase (DNA-PK) regulates the DNA damage introduced during Sleeping Beauty (SB) element excision and reinsertion in mammalian cells. Using both plasmid- and chromosome-based mobility assays, we analyzed the repair of transposase-induced double-strande...

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Publicat a:Mol Cell Biol
Autors principals: Yant, Stephen R., Kay, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262663/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14612396/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.23.8505-8518.2003
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