Nonhomologous-End-Joining Factors Regulate DNA Repair Fidelity during Sleeping Beauty Element Transposition in Mammalian Cells

Herein, we report that the DNA-dependent protein kinase (DNA-PK) regulates the DNA damage introduced during Sleeping Beauty (SB) element excision and reinsertion in mammalian cells. Using both plasmid- and chromosome-based mobility assays, we analyzed the repair of transposase-induced double-strande...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Yant, Stephen R., Kay, Mark A.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 2003
Assuntos:	DNA Dynamics and Chromosome Structure
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262663/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14612396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.23.8505-8518.2003
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