Nonhomologous-End-Joining Factors Regulate DNA Repair Fidelity during Sleeping Beauty Element Transposition in Mammalian Cells

Herein, we report that the DNA-dependent protein kinase (DNA-PK) regulates the DNA damage introduced during Sleeping Beauty (SB) element excision and reinsertion in mammalian cells. Using both plasmid- and chromosome-based mobility assays, we analyzed the repair of transposase-induced double-strande...

Celý popis

Podrobná bibliografie

Vydáno v:	Mol Cell Biol
Hlavní autoři:	Yant, Stephen R., Kay, Mark A.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 2003
Témata:	DNA Dynamics and Chromosome Structure
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262663/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14612396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.23.8505-8518.2003
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!