Strand-Specific RNA Synthesis Defects in a Poliovirus with a Mutation in Protein 3A

Substitution of a methionine residue at position 79 in poliovirus protein 3A with valine or threonine caused defective viral RNA synthesis, manifested as delayed onset and reduced yield of viral RNA, in HeLa cells transfected with a luciferase-containing replicon. Viruses containing these same mutat...

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Bibliografske podrobnosti

izdano v:	J Virol
Principais autores:	Teterina, Natalya L., Rinaudo, Mario S., Ehrenfeld, Ellie
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2003
Teme:	Replication
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262582/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14610190/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.23.12679-12691.2003
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