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Strand-Specific RNA Synthesis Defects in a Poliovirus with a Mutation in Protein 3A
Substitution of a methionine residue at position 79 in poliovirus protein 3A with valine or threonine caused defective viral RNA synthesis, manifested as delayed onset and reduced yield of viral RNA, in HeLa cells transfected with a luciferase-containing replicon. Viruses containing these same mutat...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC262582/ https://ncbi.nlm.nih.gov/pubmed/14610190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.23.12679-12691.2003 |
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