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Poliovirus 5′-Terminal Cloverleaf RNA Is Required in cis for VPg Uridylylation and the Initiation of Negative-Strand RNA Synthesis

Chimeric poliovirus RNAs, possessing the 5′ nontranslated region (NTR) of hepatitis C virus in place of the 5′ NTR of poliovirus, were used to examine the role of the poliovirus 5′ NTR in viral replication. The chimeric viral RNAs were incubated in cell-free reaction mixtures capable of supporting t...

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Detalhes bibliográficos
Main Authors: Lyons, Traci, Murray, Kenneth E., Roberts, Allan W., Barton, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114651/
https://ncbi.nlm.nih.gov/pubmed/11602711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.22.10696-10708.2001
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