Poliovirus cre(2C)-Dependent Synthesis of VPgpUpU Is Required for Positive- but Not Negative-Strand RNA Synthesis

The cre(2C) hairpin is a cis-acting replication element in poliovirus RNA and serves as a template for the synthesis of VPgpUpU. We investigated the role of the cre(2C) hairpin on VPgpUpU synthesis and viral RNA replication in preinitiation RNA replication complexes isolated from HeLa S10 translatio...

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Detalhes bibliográficos
Main Authors: Morasco, B. Joan, Sharma, Nidhi, Parilla, Jessica, Flanegan, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153981/
https://ncbi.nlm.nih.gov/pubmed/12692216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.9.5136-5144.2003
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