Strand-Specific RNA Synthesis Defects in a Poliovirus with a Mutation in Protein 3A

Substitution of a methionine residue at position 79 in poliovirus protein 3A with valine or threonine caused defective viral RNA synthesis, manifested as delayed onset and reduced yield of viral RNA, in HeLa cells transfected with a luciferase-containing replicon. Viruses containing these same mutat...

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Pubblicato in:	J Virol
Autori principali:	Teterina, Natalya L., Rinaudo, Mario S., Ehrenfeld, Ellie
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Replication
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262582/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14610190/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.23.12679-12691.2003
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