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Strand-Specific RNA Synthesis Defects in a Poliovirus with a Mutation in Protein 3A

Substitution of a methionine residue at position 79 in poliovirus protein 3A with valine or threonine caused defective viral RNA synthesis, manifested as delayed onset and reduced yield of viral RNA, in HeLa cells transfected with a luciferase-containing replicon. Viruses containing these same mutat...

詳細記述

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書誌詳細
主要な著者: Teterina, Natalya L., Rinaudo, Mario S., Ehrenfeld, Ellie
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC262582/
https://ncbi.nlm.nih.gov/pubmed/14610190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.23.12679-12691.2003
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