Neutralization of Infectivity of Diverse R5 Clinical Isolates of Human Immunodeficiency Virus Type 1 by gp120-Binding 2′F-RNA Aptamers

Human immunodeficiency virus type 1 (HIV-1) has evolved a number of strategies to resist current antiretroviral drugs and the selection pressures of humoral and cellular adaptive immunity. For example, R5 strains, which use the CCR5 coreceptor for entry and are the dominant viral phenotype for HIV-1...

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Hlavní autoři: Khati, Makobetsa, Schüman, Michael, Ibrahim, Jamal, Sattentau, Quentin, Gordon, Siamon, James, William
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC262555/
https://ncbi.nlm.nih.gov/pubmed/14610191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.23.12692-12698.2003
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