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Cytotoxicological Analysis of a gp120 Binding Aptamer with Cross-Clade Human Immunodeficiency Virus Type 1 Entry Inhibition Properties: Comparison to Conventional Antiretrovirals

The long-term cumulative cytotoxicity of antiretrovirals (ARVs) is among the major causes of treatment failure in patients infected with human immunodeficiency virus (HIV) and patients with AIDS. This calls for the development of novel ARVs with less or no cytotoxicity. In the present study, we comp...

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Detalhes bibliográficos
Main Authors: de Campos, Walter Rangel Lopes, Coopusamy, Dayaneethie, Morris, Lynn, Mayosi, Bongani M., Khati, Makobetsa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704642/
https://ncbi.nlm.nih.gov/pubmed/19364860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01502-08
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