Cytotoxicological Analysis of a gp120 Binding Aptamer with Cross-Clade Human Immunodeficiency Virus Type 1 Entry Inhibition Properties: Comparison to Conventional Antiretrovirals

The long-term cumulative cytotoxicity of antiretrovirals (ARVs) is among the major causes of treatment failure in patients infected with human immunodeficiency virus (HIV) and patients with AIDS. This calls for the development of novel ARVs with less or no cytotoxicity. In the present study, we comp...

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Bibliographische Detailangaben
Hauptverfasser: de Campos, Walter Rangel Lopes, Coopusamy, Dayaneethie, Morris, Lynn, Mayosi, Bongani M., Khati, Makobetsa
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704642/
https://ncbi.nlm.nih.gov/pubmed/19364860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01502-08
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