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Differential intra-endothelial delivery of polymer nanocarriers targeted to distinct PECAM-1 epitopes

Coupling drug carriers to antibodies for targeting endothelial cells (ECs) may improve treatment of vascular and pulmonary diseases. Selecting antibodies that deliver carriers to the cell surface or intracellularly may further optimize specifcity of interventions. We studied antibody-directed target...

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Main Authors: Garnacho, Carmen, Albelda, Steven M., Muzykantov, Vladimir R., Muro, Silvia
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615664/
https://ncbi.nlm.nih.gov/pubmed/18606202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2008.06.007
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