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Differential intra-endothelial delivery of polymer nanocarriers targeted to distinct PECAM-1 epitopes

Coupling drug carriers to antibodies for targeting endothelial cells (ECs) may improve treatment of vascular and pulmonary diseases. Selecting antibodies that deliver carriers to the cell surface or intracellularly may further optimize specifcity of interventions. We studied antibody-directed target...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Garnacho, Carmen, Albelda, Steven M., Muzykantov, Vladimir R., Muro, Silvia
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615664/
https://ncbi.nlm.nih.gov/pubmed/18606202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2008.06.007
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