Endothelial Targeting of Semi-permeable Polymer Nanocarriers for Enzyme Therapies

The medical utility of proteins, e.g. therapeutic enzymes, is greatly restricted by their liable nature and inadequate delivery. Most therapeutic enzymes do not accumulate in their targets and are inactivated by proteases. Targeting of enzymes encapsulated into substrate-permeable Polymeric Nano-Car...

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Detalhes bibliográficos
Main Authors: Dziubla, Thomas D, Shuvaev, Vladimir V., Hong, Nan Kang, Hawkins, Brian, Muniswamy, Madesh, Takano, Hajime, Simone, Eric, Nakada, Marian T., Fisher, Aron, Albelda, Steven M., Muzykantov, Vladimir R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132444/
https://ncbi.nlm.nih.gov/pubmed/17950837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2007.09.023
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