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Filamentous polymer nanocarriers of tunable stiffness that encapsulate the therapeutic enzyme catalase

Therapeutic proteins are prone to inactivation by aggregation, proteases and natural inhibitors, motivating development of protective delivery systems. Here we focus on protective encapsulation of the potent antioxidant enzyme, catalase, by filamentous polymer nanocarriers (f-PNC), with the specific...

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Bibliographic Details
Main Authors: Simone, Eric A., Dziubla, Thomas D., Discher, Dennis E., Muzykantov, Vladimir R.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720640/
https://ncbi.nlm.nih.gov/pubmed/19385657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm900189x
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