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Filamentous polymer nanocarriers of tunable stiffness that encapsulate the therapeutic enzyme catalase

Therapeutic proteins are prone to inactivation by aggregation, proteases and natural inhibitors, motivating development of protective delivery systems. Here we focus on protective encapsulation of the potent antioxidant enzyme, catalase, by filamentous polymer nanocarriers (f-PNC), with the specific...

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Detalles Bibliográficos
Autores principales: Simone, Eric A., Dziubla, Thomas D., Discher, Dennis E., Muzykantov, Vladimir R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720640/
https://ncbi.nlm.nih.gov/pubmed/19385657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm900189x
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