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Filamentous polymer nanocarriers of tunable stiffness that encapsulate the therapeutic enzyme catalase

Therapeutic proteins are prone to inactivation by aggregation, proteases and natural inhibitors, motivating development of protective delivery systems. Here we focus on protective encapsulation of the potent antioxidant enzyme, catalase, by filamentous polymer nanocarriers (f-PNC), with the specific...

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Detalhes bibliográficos
Main Authors: Simone, Eric A., Dziubla, Thomas D., Discher, Dennis E., Muzykantov, Vladimir R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720640/
https://ncbi.nlm.nih.gov/pubmed/19385657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm900189x
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