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Flow shear stress differentially regulates endothelial uptake of nanocarriers targeted to distinct epitopes of PECAM-1

Targeting nanocarriers (NC to endothelial cell adhesion molecules including Platelet-Endothelial Cell Adhesion Molecule-1 (PECAM-1 or CD31) improves drug delivery and pharmacotherapy of inflammation, oxidative stress, thrombosis and ischemia in animal models. Recent studies unveiled that hydrodynami...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Han, Jingyan, Shuvaev, Vladimir V., Davies, Peter F., Eckmann, David M., Muro, Silvia, Muzykantov, Vladimir R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793278/
https://ncbi.nlm.nih.gov/pubmed/25966362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.05.006
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