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The Substrate Recognition Domains of the N-end Rule Pathway

The N-end rule pathway is a ubiquitin-dependent system where E3 ligases called N-recognins, including UBR1 and UBR2, recognize type-1 (basic) and type-2 (bulky hydrophobic) N-terminal residues as part of N-degrons. We have recently reported an E3 family (termed UBR1 through UBR7) characterized by th...

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Detalhes bibliográficos
Main Authors: Tasaki, Takafumi, Zakrzewska, Adriana, Dudgeon, Drew D., Jiang, Yonghua, Lazo, John S., Kwon, Yong Tae
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615520/
https://ncbi.nlm.nih.gov/pubmed/19008229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803641200
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