RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

The ATE1-encoded Arg-transferase mediates conjugation of Arg to N-terminal Asp, Glu, and Cys of certain eukaryotic proteins, yielding N-terminal Arg that can act as a degradation signal for the ubiquitin-dependent N-end rule pathway. We have previously shown that mouse ATE1(–/–) embryos die with def...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Min Jae, Tasaki, Takafumi, Moroi, Kayoko, An, Jee Young, Kimura, Sadao, Davydov, Ilia V., Kwon, Yong Tae
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1257735/
https://ncbi.nlm.nih.gov/pubmed/16217033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507533102
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