Side Chain Oxygenated Cholesterol Regulates Cellular Cholesterol Homeostasis through Direct Sterol-Membrane Interactions

Side chain oxysterols exert cholesterol homeostatic effects by suppression of sterol regulatory element-binding protein maturation and promoting degradation of hydroxymethylglutaryl-CoA reductase. To examine whether oxysterol-membrane interactions contribute to the regulation of cellular cholesterol...

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Bibliografische gegevens
Hoofdauteurs: Gale, Sarah E., Westover, Emily J., Dudley, Nicole, Krishnan, Kathiresan, Merlin, Sean, Scherrer, David E., Han, Xianlin, Zhai, Xiuhong, Brockman, Howard L., Brown, Rhoderick E., Covey, Douglas F., Schaffer, Jean E., Schlesinger, Paul, Ory, Daniel S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2009
Onderwerpen:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615513/
https://ncbi.nlm.nih.gov/pubmed/18996837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807210200
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