Side Chain Oxygenated Cholesterol Regulates Cellular Cholesterol Homeostasis through Direct Sterol-Membrane Interactions

Side chain oxysterols exert cholesterol homeostatic effects by suppression of sterol regulatory element-binding protein maturation and promoting degradation of hydroxymethylglutaryl-CoA reductase. To examine whether oxysterol-membrane interactions contribute to the regulation of cellular cholesterol...

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Dades bibliogràfiques
Autors principals: Gale, Sarah E., Westover, Emily J., Dudley, Nicole, Krishnan, Kathiresan, Merlin, Sean, Scherrer, David E., Han, Xianlin, Zhai, Xiuhong, Brockman, Howard L., Brown, Rhoderick E., Covey, Douglas F., Schaffer, Jean E., Schlesinger, Paul, Ory, Daniel S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615513/
https://ncbi.nlm.nih.gov/pubmed/18996837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807210200
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