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Sigmatropic Rearrangements as Tools for Amino Acid and Peptide Modification: Application of the Allylic Sulfur Ylide Rearrangement to the Preparation of Neoglyco- and Other Conjugates

Reaction of S-allyl cysteine derivatives, generated by the selenocysteine ligation, with rhodium carbenoids, stabilized and unstabilized, enables the attachment of diverse functionality onto cysteine residues. The reaction is successfully applied to the introduction of lipid-like residues, a fluorou...

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Detalhes bibliográficos
Main Authors: Crich, David, Zou, Yekui, Brebion, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615470/
https://ncbi.nlm.nih.gov/pubmed/17109543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo061439y
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