Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes To Pluripotency

Pluripotent cells can be derived from fibroblasts by ectopic expression of defined transcription factors. A fundamental unresolved question is whether terminally differentiated cells can be reprogrammed to pluripotency. We utilized transgenic and inducible expression of four transcription factors (O...

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Détails bibliographiques
Auteurs principaux: Hanna, Jacob, Markoulaki, Styliani, Schorderet, Patrick, Carey, Bryce W., Beard, Caroline, Wernig, Marius, Creyghton, Menno P., Steine, Eveline J., Cassady, John P., Foreman, Ruth, Lengner, Christopher J., Dausman, Jessica A., Jaenisch., Rudolf
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615249/
https://ncbi.nlm.nih.gov/pubmed/18423197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.03.028
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