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DNA Polymerase δ Is Required for Early Mammalian Embryogenesis

BACKGROUND: In eukaryotic cells, DNA polymerase δ (Polδ), whose catalytic subunit p125 is encoded in the Pold1 gene, plays a central role in chromosomal DNA replication, repair, and recombination. However, the physiological role of the Polδ in mammalian development has not been thoroughly investigat...

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Hlavní autoři: Uchimura, Arikuni, Hidaka, Yuko, Hirabayashi, Takahiro, Hirabayashi, Masumi, Yagi, Takeshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615215/
https://ncbi.nlm.nih.gov/pubmed/19145245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004184
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