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DNA Polymerase δ Is Required for Early Mammalian Embryogenesis
BACKGROUND: In eukaryotic cells, DNA polymerase δ (Polδ), whose catalytic subunit p125 is encoded in the Pold1 gene, plays a central role in chromosomal DNA replication, repair, and recombination. However, the physiological role of the Polδ in mammalian development has not been thoroughly investigat...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615215/ https://ncbi.nlm.nih.gov/pubmed/19145245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004184 |
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