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PCNA is required for initiation of recombination-associated DNA synthesis by DNA polymerase δ

Genetic recombination ensures proper chromosome segregation during meiosis and is essential for genome stability and tumor suppression. DNA synthesis after Rad51-mediated DNA strand invasion is a crucial step during recombination. PCNA is known as the processivity clamp for DNA polymerases. Here, we...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Xuan, Stith, Carrie M., Burgers, Peter M., Heyer, Wolf-Dietrich
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784891/
https://ncbi.nlm.nih.gov/pubmed/19941829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.09.036
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