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PCNA is required for initiation of recombination-associated DNA synthesis by DNA polymerase δ
Genetic recombination ensures proper chromosome segregation during meiosis and is essential for genome stability and tumor suppression. DNA synthesis after Rad51-mediated DNA strand invasion is a crucial step during recombination. PCNA is known as the processivity clamp for DNA polymerases. Here, we...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784891/ https://ncbi.nlm.nih.gov/pubmed/19941829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.09.036 |
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