Identification of surface residues mediating tissue factor binding and catalytic function of the serine protease factor VIIa

Factor VIIa (VIIa), the serine protease that initiates the coagulation pathways, is catalytically activated upon binding to its cell surface receptor and cofactor tissue factor (TF). This study provides a comprehensive analysis of the functional surface of VIIa by alanine scanning mutagenesis of 112...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Dickinson, Craig D., Kelly, Curtis R., Ruf, Wolfram
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26140/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8962059/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.25.14379
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!