Unexpected crucial role of residue 225 in serine proteases

Residue 225 in serine proteases of the chymotrypsin family is Pro or Tyr in more than 95% of nearly 300 available sequences. Proteases with Y225 (like some blood coagulation and complement factors) are almost exclusively found in vertebrates, whereas proteases with P225 (like degradative enzymes) ar...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Guinto, Enriqueta R., Caccia, Sonia, Rose, Thierry, Fütterer, Klaus, Waksman, Gabriel, Di Cera, Enrico
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 1999
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC26700/
https://ncbi.nlm.nih.gov/pubmed/10051558
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